Reduce kidney
6. Patient-based Dose 6.4) Disease state 6.4.1) Disease State
6.4.1.1) Reduce Dose Normal 3
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The adult dose of a drug is 500 mg every 12 hours. For an elderly patient with impaired renal function, the dose is reduced to 100 mg every 6 hours. Calculate the percentage reduction in the daily dose.
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lb equals 60.00% kg
Adult total dose = `(500 mg) / (12 hr) × (24 hr) / (1 day)` = 1000 `(mg) / (day)`
Reduced total dose = `(100 mg) / (6 hr) × (24 hr) / (1 day)` = 400 `(mg) / (day)`
Amount reduced = 1000 mg – 400 mg = 600 mg
The percentage reduction in the daily dose
= `(600 mg)/(1000 mg) × 100 %` = 60.00 % Ans.
Reduced total dose = `(100 mg) / (6 hr) × (24 hr) / (1 day)` = 400 `(mg) / (day)`
Amount reduced = 1000 mg – 400 mg = 600 mg
The percentage reduction in the daily dose
= `(600 mg)/(1000 mg) × 100 %` = 60.00 % Ans.