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Reduce kidney

6. Patient-based Dose 6.4) Disease state 6.4.1) Disease State

6.4.1.1) Reduce Dose Normal 3


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The adult dose of a drug is 100 mg every 8 hours. For an elderly patient with impaired renal function, the dose is reduced to 50 mg every 6 hours. Calculate the percentage reduction in the daily dose.


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lb equals 33.33% kg

Adult total dose = `(100 mg) / (8 hr) × (24 hr) / (1 day)` = 300 `(mg) / (day)`

Reduced total dose = `(50 mg) / (6 hr) × (24 hr) / (1 day)` = 200 `(mg) / (day)`

Amount reduced = 300 mg – 200 mg = 100 mg

The percentage reduction in the daily dose

= `(100 mg)/(300 mg) × 100 %` = 33.33 % Ans.




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