Reduce kidney

6. Patient-based Dose 6.4) Disease state 6.4.1) Disease State

6.4.1.1) Reduce Dose Normal 3


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The adult dose of a drug is 600 mg every 6 hours. For an elderly patient with impaired renal function, the dose is reduced to 100 mg every 6 hours. Calculate the reduction in the daily dose, in milligrams.


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lb equals 2000.00mg kg

Adult total dose = `(600 mg) / (6 hr) × (24 hr) / (1 day)` = 2400 `(mg) / (day)`

Reduced total dose = `(100 mg) / (6 hr) × (24 hr) / (1 day)` = 400 `(mg) / (day)`

Amount reduced = 2400 mg – 400 mg = 2000 mg

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