Regimen: doxorubicin for axillary lymph node involvement following resection of primary breast cancer in combination with cyclophosphamide

6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.2) Intravenous dose of Doxorubicin

6.5.2.1) Intravenous dose per cycle of Doxorubicin Easy 1


Total tried:       Correct:       Wrong:

Regimen : Doxorubicin for axillary lymph node involvement following resection of primary breast cancer in combination with cyclophosphamide.

Cycle: 28 days, repeat every 28 days for 3-5 cycles

  • Doxorubicin, 60 mg/m2, IV bolus, D 1

For doxorubicin calculate total intravenous dose per cycle for a patient measuring 6 feet 2 inches in height and weighing 278 lb.


Click on the button below to see the answer and explanations

lb equals 154.01 mg kg

  • The patient height
    = 6 feet 2 inches
    = ( 6 × 12 + 2 ) inch
    = 74 inch
    = 74 × 2.54 cm
    = 187.96 cm

  • patient weight
    = 278 lb
    = 278 × 0.454 kg
    = 126.2 kg

  • BSA for the patient is

    BSA `= \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))`

    ` \quad \quad \quad = sqrt(( 187.96 \quad cm × 126.2 \quad Kg )/(3600)) = 2.5669 ` m2

  • For Doxorubicin :
    `( 60 \quad mg)/( 1 \quad m^2 )` × 2.5669 m2 × 1 (days of treatment)
    = 154.014 mg Ans.