### Regimen: doxorubicin for axillary lymph node involvement following resection of primary breast cancer in combination with cyclophosphamide

6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.2) Intravenous dose of Doxorubicin

6.5.2.1) Intravenous dose per cycle of Doxorubicin Easy 1

Total tried:       Correct:       Wrong:

Regimen : Doxorubicin for axillary lymph node involvement following resection of primary breast cancer in combination with cyclophosphamide.

Cycle: 28 days, repeat every 28 days for 3-5 cycles

• Doxorubicin, 60 mg/m2, IV bolus, D 1

For doxorubicin calculate total intravenous dose per cycle for a patient measuring 5 feet 9 inches in height and weighing 257 lb. Click on the button below to see the answer and explanations

lb equals 143.02 mg kg

• The patient height
= 5 feet 9 inches
= ( 5 × 12 + 9 ) inch
= 69 inch
= 69 × 2.54 cm
= 175.26 cm

• patient weight
= 257 lb
= 257 × 0.454 kg
= 116.7 kg

• BSA for the patient is

BSA = \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))

 \quad \quad \quad = sqrt(( 175.26 \quad cm × 116.7 \quad Kg )/(3600)) = 2.3836  m2

• For Doxorubicin :
( 60 \quad mg)/( 1 \quad m^2 ) × 2.3836 m2 × 1 (days of treatment)
= 143.016 mg Ans.