T02) Creatinine clearance using Jelliffe method
50. Pharmacokinetics 50.2) Plasma concentrations over time 50.2.2) Creatinine clearance
T01: Creatinine Clearance methods Normal 1
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Calculate the creatinine clearance of a 59-year old female patient with 182 lb of weight. The serum creatinine level of the patient is 1.27 mg/dL.
Jelliffe formula:
`CrCl_{m}=(98-0.8×(ag e-20))/(Serum \quad Cr)`
`CrCl_{f}=CrCl_{m} × 0.9`
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lb equals 47.339 mL/min kg
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Body weight =
182 lb = `(182 \quad lb)×(1 \quad kg)/(2.2 lb) =82.727 \quad kg`
This patient is female.
Plugging values in Jelliffe equation:
`CrCl_{f}=(98-0.8×(ag e-20))/(Serum \quad Cr)×0.9`
`∴ CrCl_{f}=(98-0.8×(59-20))/(1.27)×0.9`
`∴ CrCl_{f}=47.339`
Thus, the creatinine clearance of this patient is: 47.339 mL/min. (Ans).