Determine weight of total content from PPM from the weight of the drug
3. Percent, Ratio, mg/mL, PPM, PPB 3.4) PPM and PPB 3.4.1) PPM, PPB - General
3.4.1.1) Drug weight from PPM and total Weight Easy 1
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The potency of a preparation is 34.1 PPM. How many kilograms will this preparation weigh, if it contains 1278.75 mg of a drug?
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lb equals 37.5 Kg kg
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PPM is the number of grams present per 1 million (1,000,000) grams of the preparation or solution or mixture.
34.1 PPM means, there is 34.1 g of drug present in each million (1,000,000) g of the preparation.
Weight of drug = 1278.75 mg.
Converting it to grams `=1278.75/1000=1.27875` g.
Therefore, we can write:
`(34.1 \quad g)/(1,000,000\quad g)=(1.27875\quad g)/x therefore x = 37500` g.
Converting g into Kg:
`=37500/1000=37.5` Kg. Ans.