Dose range by body weight

6. Patient-based Dose 6.2) Body Weight 6.2.1) Body weight General

6.2.1.1) Drug dose based on body weight Easy 1


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Dosage range of a phase III drug for adult is 15 to 65 mg/kg of body weight. Calculate the usual range for a adult weighting 102 lb?


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lb equals 690 mg - 3000 mg kg


  • Simple DA method for 15 mg drug
`(15 \quad mg)/(1\quad kg) × 102 \quad lb × (0.454\quad kg)/(1\quad lb)` = 694.62 mg


  • Simple DA method for 65 mg drug
`(65 \quad mg)/(1\quad kg) × 102 \quad lb × (0.454\quad kg)/(1\quad lb)` = 3010.02 mg


Therefore, range is from 694.62 mg to 3010.02 mg actually, literatures round these numbers and express as 690 mg to 3000 mg