Dose range by body weight

6. Patient-based Dose 6.2) Body Weight 6.2.1) Body weight General

6.2.1.1) Drug dose based on body weight Easy 1


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Dosage range of Isoniazid for adult is 4 to 6 mg/kg of body weight. Calculate the usual range for a adult weighting 122 lb?


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lb equals 220 mg - 330 mg kg


  • Simple DA method for 4 mg drug
`(4 \quad mg)/(1\quad kg) × 122 \quad lb × (0.454\quad kg)/(1\quad lb)` = 221.552 mg


  • Simple DA method for 6 mg drug
`(6 \quad mg)/(1\quad kg) × 122 \quad lb × (0.454\quad kg)/(1\quad lb)` = 332.328 mg


Therefore, range is from 221.552 mg to 332.328 mg actually, literatures round these numbers and express as 220 mg to 330 mg

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