Regimen: VC for Chemotherapy

6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.1) Intravenous dose of VC

6.5.1.1)Intravenous dose per cycle of vinorelbine Normal 1


Total tried:       Correct:       Wrong:

Regimen : VC
Cycle: 28 days, repeat for 2 - 8 cycles

  • Vinorelbine, 25 mg/m2, IV , D 1,8,15,22
  • Cisplatin, 100 mg/m2, IV , D 1
For Vinorelbine calculate total intravenous dose per cycle for a patient measuring 5 feet 3 inches in height and weighing 228 lb.


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lb equals 214.49 mg kg

  • The patient height
    = 5 feet 3 inches
    = ( 5 × 12 + 3 ) inch
    = 63 inch
    = 63 × 2.54 cm
    = 160.02 cm

  • patient weight
    = 228 lb
    = 228 × 0.454 kg
    = 103.5 kg

  • BSA for the patient is

    BSA `= \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))`

    ` \quad \quad \quad = sqrt(( 160.02 \quad cm × 103.5 \quad Kg )/(3600)) = 2.1449 ` m2

  • For Vinorelbine :
    `( 25 \quad mg)/( 1 \quad m^2 )` × 2.1449 m2 × 4 (days of treatment)
    = 214.49 mg Ans.

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