Regimen: VC for Chemotherapy

6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.1) Intravenous dose of VC

6.5.1.1)Intravenous dose per cycle of vinorelbine Normal 1


Total tried:       Correct:       Wrong:

Regimen : VC
Cycle: 28 days, repeat for 2 - 8 cycles

  • Vinorelbine, 25 mg/m2, IV , D 1,8,15,22
  • Cisplatin, 100 mg/m2, IV , D 1
For Cisplatin calculate total intravenous dose per cycle for a patient measuring 5 feet 10 inches in height and weighing 317 lb.


Click on the button below to see the answer and explanations

lb equals 266.59 mg kg

  • The patient height
    = 5 feet 10 inches
    = ( 5 × 12 + 10 ) inch
    = 70 inch
    = 70 × 2.54 cm
    = 177.8 cm

  • patient weight
    = 317 lb
    = 317 × 0.454 kg
    = 143.9 kg

  • BSA for the patient is

    BSA `= \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))`

    ` \quad \quad \quad = sqrt(( 177.8 \quad cm × 143.9 \quad Kg )/(3600)) = 2.6659 ` m2

  • For Cisplatin :
    `( 100 \quad mg)/( 1 \quad m^2 )` × 2.6659 m2 × 1 (days of treatment)
    = 266.59 mg Ans.