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Regimen: Stanford V for Hodgkin lymphoma

6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.4) Intravenous dose of Stanford V

6.5.4.1) Intravenous dose per cycle of Stanford V Normal 1


Total tried:       Correct:       Wrong:

Regimen : Stanford V for Hodgkin lymphoma.
Cycle: three 4-week cycles. Total regimen is 12 weeks.

  • Doxorubicin, 25 mg/m2, IV, weeks 1, 3, 5, 7, 9 and 11
  • Mechlorethamine, 6 mg/m2, IV, weeks 1, 5 and 9
  • Vinblastine, 6 mg/m2, IV, weeks 1, 3, 5, 7, 9 and 11
  • Vincristine, 1.61 mg/m2, IV, weeks 2, 4, 6, 8, 10 and 12.
  • Bleomycin, 5 units/m2 , IV, weeks 2, 4, 6, 8, 10 and 12.
  • Etoposide, 60 mg/m2 per day IV on 2 consecutive days in weeks 3, 7, 11
  • Prednisone, 40 mg/m2 PO every other day for 10 weeks then tapered by 10 mg PO every other day between week 10 and 12
For bleomycin calculate the total intravenous dose per cycle for a patient measuring 5 feet 7 inches in height and weighing 175 lb.


Click on the button below to see the answer and explanations


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lb equals 58.16 units kg

  • The patient height
    = 5 feet 7 inches
    = ( 5 × 12 + 7 ) inch
    = 67 inch
    = 67 × 2.54 cm
    = 170.18 cm

  • patient weight
    = 175 lb
    = 175 × 0.454 kg
    = 79.5 kg

  • BSA for the patient is

    BSA `= \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))`

    ` \quad \quad \quad = sqrt(( 170.18 \quad cm × 79.5 \quad Kg )/(3600)) = 1.9386 ` m2

  • For Bleomycin :
    `( 5 \quad units)/( 1 \quad m^2 )` × 1.9386 m2 × 6 (days of treatment) = 58.16 units

`\quad \quad` Therefore,
`\quad \quad \quad` 58.16 units `Ans.`


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