Case - Ointment from Injection
3. Percent, Ratio, mg/mL, PPM, PPB 3.5) Cases 3.5.1) Cases
3.5.1.1) Case - Ointment from Injection Hard 1
Total tried: Correct: Wrong:
3. Percent, Ratio, mg/mL, PPM, PPB 3.5) Cases 3.5.1) Cases
3.5.1.1) Case - Ointment from Injection Hard 1
Total tried: Correct: Wrong:
CASE:
30 g of an ointment needs to be compounded containing 4.2% of a hydrophobic drug. The pharmacist does not have the pure form of the drug, but has an injection which he is considering to use as the source of the drug. The injection uses sesame oil as the vehicle, and his ointment will be made using cold cream base. Therefore, he concluded that he could compound the product by incorporating some amount of liquid injection into some amount of ointment base to give it the desired final weight of 30 g. The label of the injection states that 'Each 1 mL contains 75 mg of drug'. The literature search revealed that the injection has a specific gravity of 1.42.
QUESTIONS:
1. How many grams of the hydrophobic drug are needed to fill the prescription?
2. How many milliliters of the liquid injection would provide the correct amount of the drug?
3. In order to compound the product, how much cold cream base does the pharmacist need?
Click on the button below to see the answer and explanations
lb equals `1.26g; 16.8 mL and 6.14 g` kg