Determine PPM from the weight of the drug and weight of total content
3. Percent, Ratio, mg/mL, PPM, PPB 3.4) PPM and PPB 3.4.1) PPM, PPB - General
3.4.1.1) Drug weight from PPM and total Weight Easy 1
Total tried: Correct: Wrong:
8 Kg of a solution contains 140.8 mg of a therapeutic agent. Express the potency in parts per million (PPM) unit.
Click on the button below to see the answer and explanations
lb equals 17.6 PPM kg
-
PPM is the number of grams present per 1 million (1,000,000) grams of the mixture. In this case,
Weight of drug = 140.8 mg.
This should be first converted to gram unit.
`therefore` Weight of the drug in g unit = `140.8/1000=0.1408` g.
Total weight of the mixture = 8 Kg.
Converting this weight into gram unit:
Weight in g = `8 × 1000=8000` g.
Using the formula for PPM, we can write:
`(0.1408 \quad g)/(8000\quad g)=x/(1,000,000\quad g) therefore x = 17.6` g.
Therefore, the potency is 17.6 PPM. Ans.