Determine PPM from the weight of the drug and weight of total content

3. Percent, Ratio, mg/mL, PPM, PPB 3.4) PPM and PPB 3.4.1) PPM, PPB - General

3.4.1.1) Drug weight from PPM and total Weight Easy 1


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5.5 Kg of a solution contains 0.21175 g of a therapeutic agent. Express the strength in PPM unit.


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lb equals 38.5 PPM kg

    PPM is the number of grams present per 1 million (1,000,000) grams of the preparation or solution or mixture. In this case,
    Weight of drug = 0.21175 g.
    And total weight of the mixture = 5.5 Kg.
    Converting this weight into gram unit: Weight in g
    `= 5.5 × 1000=5500` g.
    Using the formula for PPM, we can write:
    `(0.21175 \quad g)/(5500\quad g)=x/(1,000,000\quad g) therefore x = 38.5` g.
    Therefore, the potency is 38.5 PPM. Ans.


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