Determine PPM from the weight of the drug and weight of total content
3. Percent, Ratio, mg/mL, PPM, PPB 3.4) PPM and PPB 3.4.1) PPM, PPB - General
3.4.1.1) Drug weight from PPM and total Weight Easy 1
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44 Kg of a solution contains 3.388 g of a therapeutic agent. Express the strength in PPM unit.
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lb equals 77 PPM kg
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PPM is the number of grams present per 1 million (1,000,000) grams of the preparation or solution or mixture. In this case,
Weight of drug = 3.388 g.
And total weight of the mixture = 44 Kg.
Converting this weight into gram unit: Weight in g
`= 44 × 1000=44000` g.
Using the formula for PPM, we can write:
`(3.388 \quad g)/(44000\quad g)=x/(1,000,000\quad g) therefore x = 77` g.
Therefore, the potency is 77 PPM. Ans.