### T03) Volume from dose and concentration

50. Pharmacokinetics 50.1) PK Basic parameters 50.1.1) Dose, Volume and Concentration

50.1.1.1) Basic parameters Easy 1

Total tried:       Correct:       Wrong:

A patient was given 61.557 mg of a drug as an IV bolus. The blood sample was obtained immediately at t_{0}, and the concentration of the drug was found 0.71 mg/L. The weight of the patient is 170 Kg. What is the volume of distribution of the drug in this patient?

Click on the button below to see the answer and explanations

Notice: Undefined variable: input_value1 in /home/jshzub/web/rxcal.org/public_html/practice/practice/includes/body.php on line 220
lb equals 86.7 L kg

Given that, amount of drug administered = (X_{0}) =61.557 mg
Since concentration is obtained by dividing the quantity of drug with total volume, we can write:
C_{0}=X_{0}/V Rightarrow V=X_{0}/C_{0}
therefore V=(61.557 \quad mg)/(0.71 \quad (mg)/L)=86.7 \quad L Ans.

#### 123 ,Lorem Ipsum dummy Text E-mail: [email protected]

Notice: Undefined index: TOTALTRY in /home/jshzub/web/rxcal.org/public_html/practice/practice/includes/body.php on line 675