T03) Volume from dose and concentration

50. Pharmacokinetics 50.1) PK Basic parameters 50.1.1) Dose, Volume and Concentration

50.1.1.1) Basic parameters Easy 1


Total tried:       Correct:       Wrong:

A patient was given 205.3688 mg of a drug as an IV bolus. The blood sample was obtained immediately at `t_{0}`, and the concentration of the drug was found 2.48 mg/L. The weight of the patient is 169 Kg. What is the volume of distribution of the drug in this patient?


Click on the button below to see the answer and explanations


Notice: Undefined variable: input_value1 in /home/jshzub/web/rxcal.org/public_html/practice/practice/includes/body.php on line 220
lb equals 82.81 L kg

    Given that, amount of drug administered = (`X_{0}`) =205.3688 mg
    Since concentration is obtained by dividing the quantity of drug with total volume, we can write:
    `C_{0}=X_{0}/V Rightarrow V=X_{0}/C_{0}`
    `therefore V=(205.3688 \quad mg)/(2.48 \quad (mg)/L)=82.81 \quad L` Ans.


Notice: Undefined index: TOTALTRY in /home/jshzub/web/rxcal.org/public_html/practice/practice/includes/body.php on line 675