Dosing by body weight for a hypothetical drug
6. Patient-based Dose 6.2) Body Weight 6.2.1) Body weight General
6.2.1.1) Drug dose based on body weight Easy 1
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A daily dose of 1 mg/kg,how many 100-mg capsules of the drug product should be dispensed to a patient weighing 220 lb if the dosage regimen calls for 16 weeks of therapy?
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lb equals 112 kg
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Here weight of patient is 100 kg or 220 lb and
Daily dose of drug is 1 mg/kg
Therefore,
Daily dose
= `100 \quad kg × 1 \quad (mg)/(kg) = 100 \quad mg `
weight of the capsule is 100 mg
patient needs
= `(100)/(100)`
= 1 capsules/day
for 16 weeks of therapy patient needs
` (1 \quad c a p s u l e s )/(day)× (7\quad day)/(week) × 16 \quad weeks `
= 112 capsules Ans.