Dosing by body weight for a hypothetical drug

6. Patient-based Dose 6.2) Body Weight 6.2.1) Body weight General

6.2.1.1) Drug dose based on body weight Easy 1


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A daily dose of 2 mg/kg,how many 90-mg capsules of the drug product should be dispensed to a patient weighing 198 lb if the dosage regimen calls for 16 weeks of therapy?


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lb equals 224 kg

    Here weight of patient is 90 kg or 198 lb and
    Daily dose of drug is 2 mg/kg

    Therefore,
    Daily dose
    = `90 \quad kg × 2 \quad (mg)/(kg) = 180 \quad mg `

    weight of the capsule is 90 mg

    patient needs
    = `(180)/(90)`
    = 2 capsules/day

    for 16 weeks of therapy patient needs
    ` (2 \quad c a p s u l e s )/(day)× (7\quad day)/(week) × 16 \quad weeks `
    = 224 capsules Ans.