Dosing by body weight for a hypothetical drug
6. Patient-based Dose 6.2) Body Weight 6.2.1) Body weight General
6.2.1.1) Drug dose based on body weight Easy 1
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A daily dose of 2 mg/kg,how many 20-mg capsules of the drug product should be dispensed to a patient weighing 88 lb if the dosage regimen calls for 10 weeks of therapy?
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lb equals 280 kg
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Here weight of patient is 40 kg or 88 lb and
Daily dose of drug is 2 mg/kg
Therefore,
Daily dose
= `40 \quad kg × 2 \quad (mg)/(kg) = 80 \quad mg `
weight of the capsule is 20 mg
patient needs
= `(80)/(20)`
= 4 capsules/day
for 10 weeks of therapy patient needs
` (4 \quad c a p s u l e s )/(day)× (7\quad day)/(week) × 10 \quad weeks `
= 280 capsules Ans.