Dosing by body weight for a hypothetical drug
6. Patient-based Dose 6.2) Body Weight 6.2.1) Body weight General
6.2.1.1) Drug dose based on body weight Easy 1
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A daily dose of 2 mg/kg,how many 80-mg capsules of the drug product should be dispensed to a patient weighing 176 lb if the dosage regimen calls for 16 weeks of therapy?
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lb equals 224 kg
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Here weight of patient is 80 kg or 176 lb and
Daily dose of drug is 2 mg/kg
Therefore,
Daily dose
= `80 \quad kg × 2 \quad (mg)/(kg) = 160 \quad mg `
weight of the capsule is 80 mg
patient needs
= `(160)/(80)`
= 2 capsules/day
for 16 weeks of therapy patient needs
` (2 \quad c a p s u l e s )/(day)× (7\quad day)/(week) × 16 \quad weeks `
= 224 capsules Ans.