Regimen: Doxorubicin for an acute lymphocytic leukemia (ALL) patient
6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.2) Intravenous dose of Doxorubicin
6.5.2.1) Intravenous dose per cycle of Doxorubicin Normal 1
Total tried: Correct: Wrong:
Regimen : Doxorubicin for an acute lymphocytic leukemia (ALL) patient
Cycle: 28 days, repeat for 4-5 cycles
- Doxorubicin, 75 mg/m2, IV , D 1
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lb equals 145.82 mg kg
- The patient height
= 4 feet 11 inches
= ( 4 × 12 + 11 ) inch
= 59 inch
= 59 × 2.54 cm
= 149.86 cm - patient weight
= 200 lb
= 200 × 0.454 kg
= 90.8 kg -
BSA for the patient is
BSA `= \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))`
` \quad \quad \quad = sqrt(( 149.86 \quad cm × 90.8 \quad Kg )/(3600)) = 1.9442 ` m2
-
For Doxorubicin :
`( 75 \quad mg)/( 1 \quad m^2 )` × 1.9442 m2 × 1 (days of treatment)
= 145.815 mg Ans.