Regimen: Doxorubicin for an acute lymphocytic leukemia (ALL) patient

6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.2) Intravenous dose of Doxorubicin

6.5.2.1) Intravenous dose per cycle of Doxorubicin Normal 1


Total tried:       Correct:       Wrong:

Regimen : Doxorubicin for an acute lymphocytic leukemia (ALL) patient
Cycle: 28 days, repeat for 3-4 cycles

  • Doxorubicin, 60 mg/m2, IV , D 1
For doxorubicin calculate total intravenous dose per cycle for a patient measuring 5 feet 3 inches in height and weighing 169 lb.


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lb equals 110.78 mg kg

  • The patient height
    = 5 feet 3 inches
    = ( 5 × 12 + 3 ) inch
    = 63 inch
    = 63 × 2.54 cm
    = 160.02 cm

  • patient weight
    = 169 lb
    = 169 × 0.454 kg
    = 76.7 kg

  • BSA for the patient is

    BSA `= \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))`

    ` \quad \quad \quad = sqrt(( 160.02 \quad cm × 76.7 \quad Kg )/(3600)) = 1.8464 ` m2

  • For Doxorubicin :
    `( 60 \quad mg)/( 1 \quad m^2 )` × 1.8464 m2 × 1 (days of treatment)
    = 110.784 mg Ans.


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