### Regimen: Doxorubicin for an acute lymphocytic leukemia (ALL) patient

6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.2) Intravenous dose of Doxorubicin

6.5.2.1) Intravenous dose per cycle of Doxorubicin Normal 1

Total tried:       Correct:       Wrong:

Regimen : Doxorubicin for an acute lymphocytic leukemia (ALL) patient
Cycle: 28 days, repeat for 4-5 cycles

• Doxorubicin, 75 mg/m2, IV , D 1
For doxorubicin calculate total intravenous dose per cycle for a patient measuring 4 feet 11 inches in height and weighing 200 lb. Click on the button below to see the answer and explanations

lb equals 145.82 mg kg

• The patient height
= 4 feet 11 inches
= ( 4 × 12 + 11 ) inch
= 59 inch
= 59 × 2.54 cm
= 149.86 cm

• patient weight
= 200 lb
= 200 × 0.454 kg
= 90.8 kg

• BSA for the patient is

BSA = \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))

 \quad \quad \quad = sqrt(( 149.86 \quad cm × 90.8 \quad Kg )/(3600)) = 1.9442  m2

• For Doxorubicin :
( 75 \quad mg)/( 1 \quad m^2 ) × 1.9442 m2 × 1 (days of treatment)
= 145.815 mg Ans.