Regimen: Doxorubicin for an acute lymphocytic leukemia (ALL) patient

6. Patient-based Dose 6.5) Chemo Dose Clculation 6.5.2) Intravenous dose of Doxorubicin

6.5.2.1) Intravenous dose per cycle of Doxorubicin Normal 1


Total tried:       Correct:       Wrong:

Regimen : Doxorubicin for an acute lymphocytic leukemia (ALL) patient
Cycle: 28 days, repeat for 4-5 cycles

  • Doxorubicin, 75 mg/m2, IV , D 1
For doxorubicin calculate total intravenous dose per cycle for a patient measuring 4 feet 11 inches in height and weighing 200 lb.


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lb equals 145.82 mg kg

  • The patient height
    = 4 feet 11 inches
    = ( 4 × 12 + 11 ) inch
    = 59 inch
    = 59 × 2.54 cm
    = 149.86 cm

  • patient weight
    = 200 lb
    = 200 × 0.454 kg
    = 90.8 kg

  • BSA for the patient is

    BSA `= \quad sqrt(( Height (cm) × Weight (Kg) )/(3600))`

    ` \quad \quad \quad = sqrt(( 149.86 \quad cm × 90.8 \quad Kg )/(3600)) = 1.9442 ` m2

  • For Doxorubicin :
    `( 75 \quad mg)/( 1 \quad m^2 )` × 1.9442 m2 × 1 (days of treatment)
    = 145.815 mg Ans.