Find drug weight from PPM and total quantity

3. Percent, Ratio, mg/mL, PPM, PPB 3.4) PPM and PPB 3.4.1) PPM, PPB - General

3.4.1.1) Drug weight from PPM and total Weight Easy 1


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How many milligrams of the active pharmaceutical ingredient will 21000 g of a preparation contain, if its strength is expressed as 62.7 PPM?


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lb equals 1316.7 mg kg

    62.7 PPM means, there is 62.7 g of drug in each 1,000,000 g of the mixture.
    The total weight of the preparation = 21000 grams. Therefore, we can write:
    `(62.7 \quad g)/(1,000,000\quad g)=x/(21000\quad g) therefore x = 1.3167` g.

    Now, this g unit has to be converted to mg.
    `(1000\quad mg)/(1\quad g)= y/(1.3167\quadg) therefore y = 1316.7` mg Ans.