T01) Creatinine clearance using Cockroft-Gault method

50. Pharmacokinetics 50.2) Plasma concentrations over time 50.2.2) Creatinine clearance

T01: Creatinine Clearance methods Normal 1


Total tried:       Correct:       Wrong:

Calculate the creatinine clearance of a 67-year old female patient with 158 lb of weight. The serum creatinine level of the patient is 0.82 mg/dL.

Cockroft-Gault formula:
`CrCl_{m}=(140-Ag e)/(Serum \quad Cr) × (Weight \quad i n \quad Kg)/72`

`CrCl_{f}=CrCl_{m} × 0.85`


Click on the button below to see the answer and explanations


Notice: Undefined variable: input_value1 in /home/jshzub/web/rxcal.org/public_html/practice/practice/includes/body.php on line 220
lb equals 75.479 mL/min kg

    Body weight =
    158 lb = `(158 \quad lb)×(1 \quad kg)/(2.2 lb) =71.818 \quad kg`
    This patient is female.
    Therefore, the formula will be:

    `CrCl_{f}=(140-Ag e)/(Serum \quad Cr) × (Weight \quad i n \quad Kg)/72 × 0.85`

    Plugging values in this:

    `CrCl_{f}=(140-67)/(0.82) × (71.818)/72 × 0.85`

    `∴ CrCl_{f}=75.479`

    Thus, the creatinine clearance of this patient is: 75.479 mL/min. (Ans).


Notice: Undefined index: TOTALTRY in /home/jshzub/web/rxcal.org/public_html/practice/practice/includes/body.php on line 675