(3) Volume from percent and drug amount
3. Percent, Ratio, mg/mL, PPM, PPB 3.1) Percent 3.1.1) Percent - General
3.1.1.1) Percent from weight and volume Easy 1
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Calculate the volume (in mL) of a sterile liquid preparation you can compound where the strength will be 1.7% w/v and the dissolved quantity of the active ingredient will be 4335 mg.
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lb equals 255 mL kg
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Percentage (w/v) means number of grams of drug present per 100 mL of the solution. Here, the strength is 1.7 %, which means, there is 1.7 g of drug dissolved per 100 mL of a sterile liquid preparation. We need to determine the volume (in mL) of a sterile liquid preparation which will contain 4335 mg (equals to `4335 mg × (1g)/(1000mg) = 4.335 g`) of the drug.
`∴ (100 \quad mL)/(1.7 \quad g) = x/(4.335 \quad g) ⇒ x = 255 \quad mL`
∴ The volume will be 255 mL (Ans).